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Toronto Blue Jays (37-38, third in the AL East) vs. Chicago Cubs (39-36, third in the NL Central)

Chicago; Friday, 2:20 p.m. EDT

PITCHING PROBABLES: Blue Jays: Kevin Gausman (4-4, 3.41 ERA, 1.03 WHIP, 86 strikeouts); Cubs: Ben Brown (3-2, 1.74 ERA, 0.97 WHIP, 61 strikeouts)

LINE: Cubs -121, Blue Jays -100; over/under is 7 1/2 runs

BOTTOM LINE: The Toronto Blue Jays will try to keep a three-game road win streak alive when they visit the Chicago Cubs.

Chicago has a 39-36 record overall and a 22-16 record in home games. The Cubs have a 31-12 record in games when they record eight or more hits.

Toronto has a 16-20 record in road games and a 37-38 record overall. The Blue Jays have gone 14-6 in games when they hit two or more home runs.

Friday’s game is the first time these teams square off this season.

TOP PERFORMERS: Pete Crow-Armstrong has 15 home runs, 25 walks and 37 RBI while hitting .276 for the Cubs. Seiya Suzuki is 12 for 36 with four doubles, a home run and eight RBI over the last 10 games.

Vladimir Guerrero Jr. has 12 doubles and four home runs for the Blue Jays. Nathan Lukes is 11 for 35 with a double, a home run and three RBI over the past 10 games.

LAST 10 GAMES: Cubs: 5-5, .246 batting average, 3.68 ERA, outscored opponents by five runs

Blue Jays: 6-4, .254 batting average, 3.80 ERA, outscored opponents by two runs

INJURIES: Cubs: Edward Cabrera: day-to-day (hand), Daniel Palencia: 15-Day IL (elbow), Matthew Boyd: 15-Day IL (knee), Jameson Taillon: 15-Day IL (hamstring), Justin Steele: 60-Day IL (elbow), Christopher Austin: 60-Day IL (knee), Hunter Harvey: 60-Day IL (tricep), Riley Martin: 15-Day IL (elbow), Porter Hodge: 60-Day IL (elbow), Shelby Miller: 60-Day IL (elbow), Cade Horton: 60-Day IL (forearm)

Blue Jays: Lenyn Sosa: 10-Day IL (wrist), Max Scherzer: 15-Day IL (back), Daulton Varsho: 10-Day IL (wrist), Lazaro Estrada: 60-Day IL (shoulder), Joe Mantiply: 60-Day IL (knee), Addison Barger: 10-Day IL (elbow), Jose Berrios: 60-Day IL (elbow), Shane Bieber: 60-Day IL (elbow), Yimi Garcia: 60-Day IL (elbow), Cody Ponce: 60-Day IL (knee), Anthony Santander: 60-Day IL (shoulder), Bowden Francis: 60-Day IL (elbow)

Baltimore Orioles (35-41, fourth in the AL East) vs. Los Angeles Dodgers (48-27, first in the NL West)

Los Angeles; Friday, 10:10 p.m. EDT

PITCHING PROBABLES: Orioles: Trey Gibson (1-2, 5.91 ERA, 1.59 WHIP, 12 strikeouts); Dodgers: Roki Sasaki (3-4, 4.76 ERA, 1.33 WHIP, 64 strikeouts)

LINE: Dodgers -198, Orioles +161; over/under is 9 1/2 runs

BOTTOM LINE: The Los Angeles Dodgers host the Baltimore Orioles to open a three-game series.

Los Angeles has a 25-12 record in home games and a 48-27 record overall. Dodgers pitchers have a collective 3.33 ERA, which leads the NL.

Baltimore has a 13-22 record in road games and a 35-41 record overall. Orioles hitters have a collective .399 slugging percentage to rank sixth in the AL.

The matchup Friday is the first meeting this season between the two clubs.

TOP PERFORMERS: Shohei Ohtani has 15 doubles, two triples and 15 home runs for the Dodgers. Freddie Freeman is 11 for 38 with two doubles and two home runs over the past 10 games.

Pete Alonso leads the Orioles with 29 extra base hits (13 doubles and 16 home runs). Gunnar Henderson is 8 for 35 with two home runs and four RBI over the last 10 games.

LAST 10 GAMES: Dodgers: 6-4, .258 batting average, 5.38 ERA, outscored opponents by three runs

Orioles: 4-6, .235 batting average, 4.25 ERA, outscored by five runs

INJURIES: Dodgers: Brock Stewart: 15-Day IL (foot), Gavin Stone: 60-Day IL (shoulder), Ben Casparius: 60-Day IL (shoulder), Will Smith: 10-Day IL (neck), Tyler Glasnow: 60-Day IL (back), Brusdar Graterol: 60-Day IL (shoulder), Bobby Miller: 60-Day IL (shoulder), Blake Snell: 60-Day IL (elbow), Teoscar Hernandez: 10-Day IL (hamstring), Kike Hernandez: 10-Day IL (oblique), Landon Knack: 60-Day IL (chest), Edwin Diaz: 60-Day IL (elbow), Jake Cousins: 60-Day IL (elbow), Evan Phillips: 60-Day IL (elbow)

Orioles: Dylan Beavers: 10-Day IL (oblique), Cade Povich: 15-Day IL (elbow), Yaramil Hiraldo: 60-Day IL (shoulder), Chris Bassitt: 15-Day IL (back), Zach Eflin: 60-Day IL (elbow), Dean Kremer: 60-Day IL (quadricep), Felix Bautista: 60-Day IL (shoulder), Colin Selby: 60-Day IL (shoulder), Jordan Westburg: 60-Day IL (ucl), Ryan Mountcastle: 60-Day IL (foot)

Chicago White Sox (39-34, first in the AL Central) vs. Detroit Tigers (30-44, fifth in the AL Central)

Detroit; Friday, 6:40 p.m. EDT

PITCHING PROBABLES: White Sox: Erick Fedde (2-5, 4.50 ERA, 1.41 WHIP, 44 strikeouts); Tigers: Tarik Skubal (3-3, 2.81 ERA, 0.98 WHIP, 49 strikeouts)

LINE: Tigers -246, White Sox +197; over/under is 8 runs

BOTTOM LINE: The Detroit Tigers open a three-game series at home against the Chicago White Sox on Friday.

Detroit has an 18-16 record at home and a 30-44 record overall. The Tigers are 12-29 in games when they have allowed a home run.

Chicago has gone 15-22 in road games and 39-34 overall. The White Sox are second in the AL with 102 total home runs, averaging 1.4 per game.

The matchup Friday is the fourth time these teams square off this season.

TOP PERFORMERS: Dillon Dingler leads the Tigers with 16 home runs while slugging .522. Gleyber Torres is 13 for 37 with four doubles, a home run and six RBI over the past 10 games.

Miguel Vargas has 12 doubles, a triple and 16 home runs for the White Sox. Chase Meidroth is 12 for 38 with a double and a home run over the last 10 games.

LAST 10 GAMES: Tigers: 4-6, .206 batting average, 3.24 ERA, outscored opponents by 11 runs

White Sox: 6-4, .233 batting average, 5.11 ERA, outscored by eight runs

INJURIES: Tigers: Wenceel Perez: day-to-day (face), Gleyber Torres: 10-Day IL (oblique), Jack Flaherty: 15-Day IL (leg), Javier Baez: 60-Day IL (ankle), Bailey Horn: 60-Day IL (elbow), Trey Sweeney: 60-Day IL (shoulder), Burch Smith: 15-Day IL (shoulder), Brant Hurter: 60-Day IL (back), Justin Verlander: 60-Day IL (hip), Reese Olson: 60-Day IL (shoulder), Parker Meadows: 60-Day IL (head/arm), Jackson Jobe: 60-Day IL (elbow)

White Sox: Everson Pereira: 7-Day IL (concussion), Sean Newcomb: day-to-day (tricep), Jordan Hicks: 15-Day IL (lat), Tyler Gilbert: 15-Day IL (shoulder), Noah Schultz: 15-Day IL (knee), Austin Hays: 60-Day IL (calf), Munetaka Murakami: 10-Day IL (hamstring), Jordan Leasure: 60-Day IL (flexor), Ky Bush: 60-Day IL (elbow), Kyle Teel: 60-Day IL (hamstring), Drew Thorpe: 60-Day IL (elbow), Tanner Murray: 60-Day IL (shoulder), Brooks Baldwin: 60-Day IL (elbow), Mike Vasil: 60-Day IL (elbow), Prelander Berroa: 60-Day IL (elbow)

Pittsburgh Pirates (38-37, fourth in the NL Central) vs. Colorado Rockies (28-47, fifth in the NL West)

Denver; Friday, 8:40 p.m. EDT

PITCHING PROBABLES: Pirates: Bubba Chandler (2-7, 4.76 ERA, 1.38 WHIP, 68 strikeouts); Rockies: Kyle Freeland (1-7, 7.98 ERA, 1.71 WHIP, 49 strikeouts)

LINE: Pirates -141, Rockies +116; over/under is 11 1/2 runs

BOTTOM LINE: The Colorado Rockies open a three-game series at home against the Pittsburgh Pirates on Friday.

Colorado has gone 14-20 at home and 28-47 overall. The Rockies have hit 81 total home runs to rank ninth in the NL.

Pittsburgh is 18-18 in road games and 38-37 overall. The Pirates have the sixth-ranked team slugging percentage in the NL at .408.

The matchup Friday is the fourth time these teams square off this season.

TOP PERFORMERS: Troy Johnston has a .312 batting average to lead the Rockies, and has 21 doubles and three home runs. Willi Castro is 15 for 38 with two home runs and nine RBI over the past 10 games.

Nick Gonzales leads the Pirates with a .293 batting average, and has 11 doubles, two home runs, 16 walks and 32 RBI. Bryan Reynolds is 15 for 40 with four home runs and eight RBI over the last 10 games.

LAST 10 GAMES: Rockies: 4-6, .289 batting average, 6.17 ERA, outscored opponents by one run

Pirates: 4-6, .260 batting average, 5.32 ERA, outscored by 17 runs

INJURIES: Rockies: McCade Brown: 60-Day IL (shoulder), Chase Dollander: 60-Day IL (elbow), Brenton Doyle: 10-Day IL (oblique), Mickey Moniak: 10-Day IL (ankle), Tanner Gordon: 15-Day IL (hip), Jordan Beck: 10-Day IL (hamstring), Kris Bryant: 60-Day IL (back), Welinton Herrera: 60-Day IL (elbow), Jose Quintana: 60-Day IL (elbow), Pierson Ohl: 60-Day IL (elbow), RJ Petit: 60-Day IL (elbow)

Pirates: Wilber Dotel: 15-Day IL (lat), Konnor Griffin: 10-Day IL (flexor tendon), Oneil Cruz: 10-Day IL (hand), Chris Devenski: 60-Day IL (illness)

Minnesota Twins (36-40, third in the AL Central) vs. Arizona Diamondbacks (38-36, third in the NL West)

Phoenix; Friday, 9:45 p.m. EDT

PITCHING PROBABLES: Twins: Connor Prielipp (2-4, 5.26 ERA, 1.35 WHIP, 51 strikeouts); Diamondbacks: Mike Soroka (8-3, 3.11 ERA, 1.07 WHIP, 79 strikeouts)

LINE: Diamondbacks -175, Twins +143; over/under is 8 1/2 runs

BOTTOM LINE: The Arizona Diamondbacks host the Minnesota Twins on Friday to start a three-game series.

Arizona has a 38-36 record overall and a 23-15 record at home. The Diamondbacks are 27-7 in games when they scored five or more runs.

Minnesota has a 16-21 record in road games and a 36-40 record overall. The Twins are 7-11 in games decided by one run.

Friday’s game is the first time these teams match up this season.

TOP PERFORMERS: Ketel Marte has 15 doubles, two triples, 11 home runs and 43 RBI while hitting .258 for the Diamondbacks. Gabriel Moreno is 13 for 36 with three doubles and three home runs over the last 10 games.

Byron Buxton has 13 doubles, a triple and 23 home runs for the Twins. Josh Bell is 14 for 38 with two doubles, three home runs and 13 RBI over the past 10 games.

LAST 10 GAMES: Diamondbacks: 5-5, .220 batting average, 3.98 ERA, outscored by five runs

Twins: 6-4, .284 batting average, 5.93 ERA, outscored opponents by one run

INJURIES: Diamondbacks: Corbin Burnes: 60-Day IL (elbow), Cristian Mena: 60-Day IL (shoulder), Carlos Santana: 60-Day IL (groin), James McCann: 10-Day IL (quadricep), A.J. Puk: 60-Day IL (elbow), Blake Walston: 60-Day IL (elbow), Andrew Saalfrank: 60-Day IL (shoulder), Justin Martinez: 60-Day IL (elbow)

Twins: Bailey Ober: 15-Day IL (elbow), Cole Sands: 15-Day IL (forearm), Mick Abel: 15-Day IL (elbow), Kendry Rojas: 15-Day IL (elbow), David Festa: 60-Day IL (shoulder), Garrett Acton: 60-Day IL (shoulder), Ryan Jeffers: 10-Day IL (hand), Pablo Lopez: 60-Day IL (elbow)

Cleveland Guardians (40-35, second in the AL Central) vs. Houston Astros (35-41, fourth in the AL West)

Houston; Friday, 8:10 p.m. EDT

PITCHING PROBABLES: Guardians: Tanner Bibee (2-7, 3.96 ERA, 1.18 WHIP, 71 strikeouts); Astros: Tatsuya Imai (3-3, 6.43 ERA, 1.51 WHIP, 37 strikeouts)

LINE: Astros -125, Guardians +103; over/under is 8 1/2 runs

BOTTOM LINE: The Houston Astros start a three-game series at home against the Cleveland Guardians on Friday.

Houston has a 35-41 record overall and an 18-20 record in home games. The Astros are 17-36 in games when they have allowed a home run.

Cleveland is 21-18 on the road and 40-35 overall. The Guardians are 17-7 in games when they did not give up a home run.

Friday’s game is the fourth time these teams meet this season.

TOP PERFORMERS: Christian Walker has 14 doubles, a triple, 18 home runs and 52 RBI while hitting .246 for the Astros. Yordan Alvarez is 15 for 40 with two doubles and two home runs over the past 10 games.

Steven Kwan has eight doubles, a home run and 13 RBI while hitting .213 for the Guardians. Jose Ramirez is 10 for 39 with a double and two home runs over the last 10 games.

LAST 10 GAMES: Astros: 5-5, .214 batting average, 4.55 ERA, outscored by 17 runs

Guardians: 4-6, .211 batting average, 4.19 ERA, outscored by 12 runs

INJURIES: Astros: Nick Allen: 10-Day IL (hamstring), Lance McCullers: 15-Day IL (shoulder), Bennett Sousa: 15-Day IL (elbow), LaMonte Wade: 10-Day IL (hamstring), Cristian Javier: 60-Day IL (shoulder), Braden Shewmake: 10-Day IL (groin), Carlos Correa: 60-Day IL (ankle), Brandon Walter: 60-Day IL (elbow), Ronel Blanco: 60-Day IL (elbow), Hayden Wesneski: 60-Day IL (elbow)

Guardians: Chase DeLauter: 10-Day IL (rib), Angel Martinez: 10-Day IL (foot), Jose Ramirez: 10-Day IL (hand), Erik Sabrowski: 15-Day IL (elbow)

San Diego Padres (38-35, second in the NL West) vs. Texas Rangers (35-39, third in the AL West)

Arlington, Texas; Friday, 8:05 p.m. EDT

PITCHING PROBABLES: Padres: Randy Vasquez (6-4, 3.63 ERA, 1.32 WHIP, 58 strikeouts); Rangers: Jacob deGrom (5-4, 3.17 ERA, 0.99 WHIP, 89 strikeouts)

LINE: Rangers -164, Padres +134; over/under is 7 runs

BOTTOM LINE: The Texas Rangers look to stop a three-game losing streak when they play the San Diego Padres.

Texas is 17-17 at home and 35-39 overall. The Rangers have the 10th-ranked team on-base percentage in the AL at .316.

San Diego is 38-35 overall and 19-16 on the road. The Padres have the fourth-ranked team ERA in the NL at 3.85.

The matchup Friday is the first meeting this season between the two clubs.

TOP PERFORMERS: Josh Jung has eight home runs, 21 walks and 30 RBI while hitting .301 for the Rangers. Jake Burger is 13 for 34 with two doubles, two home runs and five RBI over the past 10 games.

Fernando Tatis Jr. has two home runs, 28 walks and 26 RBI while hitting .284 for the Padres. Jackson Merrill is 12 for 43 with two doubles, a triple, two home runs and six RBI over the past 10 games.

LAST 10 GAMES: Rangers: 4-6, .279 batting average, 5.22 ERA, outscored by 16 runs

Padres: 5-5, .242 batting average, 3.44 ERA, outscored opponents by five runs

INJURIES: Rangers: Danny Jansen: 10-Day IL (forearm), Chris Martin: 15-Day IL (shoulder), Corey Seager: day-to-day (concussion), Michael Helman: 10-Day IL (hand), Evan Carter: 10-Day IL (oblique), Carter Baumler: 60-Day IL (ribs), Cody Bradford: 60-Day IL (elbow), Jalen Beeks: 10-Day IL (back), Robert Garcia: 60-Day IL (shoulder), Jordan Montgomery: 60-Day IL (elbow)

Padres: Luis Campusano: 10-Day IL (toe), Freddy Fermin: 7-Day IL (concussion), Miguel Andujar: 10-Day IL (hamstring), Nick Pivetta: 60-Day IL (elbow), Matt Waldron: 15-Day IL (arm), Jake Cronenworth: 7-Day IL (concussion), German Marquez: 15-Day IL (forearm), Joe Musgrove: 60-Day IL (elbow), Jeremiah Estrada: 15-Day IL (knee), Ramon Laureano: 60-Day IL (hip), Bryan Hoeing: 60-Day IL (elbow)

Los Angeles Angels (30-46, fifth in the AL West) vs. Athletics (37-38, second in the AL West)

West Sacramento, California; Friday, 9:40 p.m. EDT

PITCHING PROBABLES: Angels: Jose Soriano (8-4, 2.79 ERA, 1.23 WHIP, 92 strikeouts); Athletics: Jeffrey Springs (3-7, 5.13 ERA, 1.32 WHIP, 68 strikeouts)

LINE: Athletics -169, Angels +139; over/under is 10 runs

BOTTOM LINE: The Athletics lead 1-0 in a four-game series with the Los Angeles Angels.

The Athletics have a 37-38 record overall and a 17-21 record at home. The Athletics have gone 15-7 in games when they did not give up a home run.

Los Angeles is 30-46 overall and 13-26 on the road. The Angels have a 21-9 record in games when they scored at least five runs.

Friday’s game is the sixth time these teams match up this season. The Athletics have a 4-1 advantage in the season series.

TOP PERFORMERS: Shea Langeliers has 15 doubles, 19 home runs and 39 RBI while hitting .276 for the Athletics. Nick Kurtz is 15 for 40 with two doubles and six home runs over the last 10 games.

LAST 10 GAMES: Athletics: 6-4, .292 batting average, 6.77 ERA, outscored by three runs

Angels: 5-5, .265 batting average, 3.24 ERA, outscored opponents by seven runs

INJURIES: Athletics: Luis Severino: 15-Day IL (shoulder), Brooks Kriske: 60-Day IL (shoulder), Brent Rooker: 10-Day IL (knee), Denzel Clarke: 60-Day IL (foot), Gunnar Hoglund: 60-Day IL (knee)

Angels: Adam Frazier: 10-Day IL (elbow), Mike Trout: 10-Day IL (hamstring), Gustavo Campero: 10-Day IL (hand), Grayson Rodriguez: 15-Day IL (back), Jorge Soler: 10-Day IL (hip), Travis d’Arnaud: 60-Day IL (foot), Sebastian Rivero: 10-Day IL (hand), Yoan Moncada: 60-Day IL (knee), Jack Kochanowicz: 60-Day IL (elbow), Robert Stephenson: 60-Day IL (elbow), Ben Joyce: 60-Day IL (shoulder), Yusei Kikuchi: 60-Day IL (shoulder), Anthony Rendon: 60-Day IL (hip)

Washington Nationals (39-36, third in the NL East) vs. Tampa Bay Rays (41-30, second in the AL East)

St. Petersburg, Florida; Friday, 7:10 p.m. EDT

PITCHING PROBABLES: Nationals: Cade Cavalli (4-4, 3.98 ERA, 1.39 WHIP, 81 strikeouts); Rays: Griffin Jax (1-5, 3.68 ERA, 1.36 WHIP, 41 strikeouts)

LINE: Rays -132, Nationals +108; over/under is 8 runs

BOTTOM LINE: The Tampa Bay Rays begin a three-game series at home against the Washington Nationals on Friday.

Tampa Bay is 41-30 overall and 24-9 in home games. The Rays have a 29-10 record in games when they record eight or more hits.

Washington has gone 23-14 on the road and 39-36 overall. The Nationals rank third in the NL with 96 total home runs, averaging 1.3 per game.

Friday’s game is the first meeting between these teams this season.

TOP PERFORMERS: Junior Caminero leads the Rays with 15 home runs while slugging .485. Jonathan Aranda is 11 for 40 with a double and four RBI over the past 10 games.

James Wood has 17 doubles and 20 home runs for the Nationals. Nasim Nunez is 13 for 33 with a double, two triples and seven RBI over the last 10 games.

LAST 10 GAMES: Rays: 4-6, .249 batting average, 3.86 ERA, outscored by five runs

Nationals: 6-4, .257 batting average, 5.01 ERA, outscored opponents by seven runs

INJURIES: Rays: Jon Heasley: 60-Day IL (elbow), Michael Grove: 60-Day IL (shoulder), Jesse Scholtens: 15-Day IL (wrist), Manuel Rodriguez: 60-Day IL (elbow), Jonny Deluca: 10-Day IL (hamstring), Steven Wilson: 60-Day IL (back), Gavin Lux: 60-Day IL (shoulder), Jake Fraley: 10-Day IL (groin), Ryan Pepiot: 60-Day IL (hip), Edwin Uceta: 60-Day IL (shoulder)

Nationals: Max Kranick: 60-Day IL (elbow), Jake Irvin: 15-Day IL (shoulder), Trevor Williams: 60-Day IL (elbow), Ken Waldichuk: 60-Day IL (forearm), Josiah Gray: 60-Day IL (elbow), DJ Herz: 60-Day IL (elbow)

Cincinnati Reds (35-38, fifth in the NL Central) vs. New York Yankees (45-28, first in the AL East)

New York; Friday, 7:05 p.m. EDT

PITCHING PROBABLES: Reds: Rhett Lowder (3-3, 4.60 ERA, 1.43 WHIP, 37 strikeouts); Yankees: Cam Schlittler (7-3, 1.82 ERA, 0.91 WHIP, 96 strikeouts)

LINE: Yankees -287, Reds +226; over/under is 8 1/2 runs

BOTTOM LINE: The New York Yankees begin a three-game series at home against the Cincinnati Reds on Friday.

New York is 45-28 overall and 21-13 at home. The Yankees have the sixth-best team on-base percentage in MLB play at .332.

Cincinnati has gone 16-19 in road games and 35-38 overall. The Reds are 19-31 in games when they have given up a home run.

Friday’s game is the first meeting between these teams this season.

TOP PERFORMERS: Ben Rice leads the Yankees with 20 home runs while slugging .606. Paul Goldschmidt is 17 for 43 with four home runs and 13 RBI over the past 10 games.

Sal Stewart leads the Reds with 14 home runs while slugging .456. Blake Dunn is 12 for 45 with two doubles, a home run and two RBI over the past 10 games.

LAST 10 GAMES: Yankees: 8-2, .276 batting average, 3.60 ERA, outscored opponents by 27 runs

Reds: 4-6, .218 batting average, 3.53 ERA, outscored by three runs

INJURIES: Yankees: Jazz Chisholm: day-to-day (groin), Austin Wells: 10-Day IL (cervical headaches), Max Fried: 15-Day IL (elbow), Trent Grisham: 10-Day IL (hamstring), Giancarlo Stanton: 10-Day IL (leg), Aaron Judge: 10-Day IL (rib), Clarke Schmidt: 60-Day IL (elbow)

Reds: Elly De La Cruz: 10-Day IL (hamstring), Ke’Bryan Hayes: 10-Day IL (back), Pierce Johnson: 15-Day IL (elbow), Emilio Pagan: 15-Day IL (hamstring), Graham Ashcraft: 60-Day IL (forearm), Brandon Williamson: 60-Day IL (shoulder), Hunter Greene: 60-Day IL (elbow)